Obsgynaecritcare

082 – Anti-NMDA receptor encephalitis with Graeme

Informações:

Synopsis

Hypothetical Case: A gynaecologist contacts you as the duty anesthetist to book an emergency laparoscopic oophorectomy. They tell you that the patient is a young woman who is currently intubated and ventilated on the intensive care unit after presenting 2 days earlier with a complex neurological syndrome, complicated by seizures requiring intubation. The surgeon tells you the ICU team have done some investigations, including an ultrasound demonstrating a complex ovarian mass, and CSF on a lumbar puncture positive for anti-NMDA receptor antibodies. What is Anti-NMDA receptor encephalitis? Why is it associated with gynaecology? When & how was it first discovered? Join Graeme and I as we discuss the ins/outs of this fascinating condition and share a few personal anecdotes of patient's we have encountered with this project. LINKS Pregnancy outcomes in anti-NMDA receptor encephalitis Acute psychiatric illness in a young woman: an unusual form of encephalitis MJA 2009 Josep Dalmau: exploring t