Science History Podcast

Human health and environmental health are inextricably linked. We are negatively impacted by the same pollutants that harm other organisms, and we all live in a sea of synthetic chemicals that are part of our food supply, personal care products, the built environment, and just about every aspect of our lives. With us to gain a better understanding of the history of environmental health, especially the impact of pollutants on human health, is Linda Birnbaum. Linda received a B.A. in biology from the University of Rochester in 1967, and M.S. and Ph.D. degrees in microbiology from the University of Illinois in 1969 and 1972. She held various research and administrative positions in academia and government before taking on the directorships of the US National Institute of Environmental Health Sciences and the National Toxicology Program in 2009. She retired from these directorships in 2019. Linda has published over 600 scientific articles, and is the recipient of numerous awards related to public health.

How is it that corporations routinely and successfully obfuscate science and seed public doubt on issues of paramount importance, ranging from climate change to health effects of tobacco and pesticides? Who are the scientists for hire whose job is to muddy the waters on important policy issues? Why doesn’t our government protect us from nefarious corporations that threaten our health and the environment, and how can we change regulatory ethics to favor the public interest? With us to answer these questions is my guest, David Michaels. David is a professor of epidemiology in the Department of Environmental and Occupational Health at George Washington University. From 1998 through 2001, David served as the Assistant Secretary for Environment, Safety and Health at the U.S. Department of Energy, with responsibility for the safety of workers, communities and the environment surrounding nuclear weapons facilities. From 2009 to 2017, David served as the 12th Assistant Secretary of OSHA, the Occupational Safety and H

Whistleblowers are admired or vilified. They are saviors of democracy or traitors to their country. They confront those in power and drive the news, and some, such as Edward Snowden and Chelsea Manning, are household names. But one man is their inspiration, the person who made whistleblowing a phenomenon of modern times, and his name is Daniel Ellsberg. Ellsberg was born in 1931 in Chicago and grew up in Detroit. He graduated with honors from Harvard with an AB in economics in 1952, and then studied at the University of Cambridge. He served in the U.S. Marine Corps from 1954-1957, and then returned to Harvard where he completed his PhD in economics in 1962. Ellsberg worked as a strategic analyst at the RAND Corporation beginning in 1958, and then in the Pentagon beginning in 1964 under Secretary of Defense Robert McNamara. He worked for the U.S. State Department in South Vietnam for two years, and then returned to the RAND Corporation. At the end of 1969, with help from his colleague Anthony Russo, Ellsberg s

Pete Myers interviews me about my new book, The Chemical Age, published this month by the University of Chicago Press.

Why is it that decades after scientists discover problems of paramount importance, such as global climate change or lead pollution, those problems still persist? Why do corporations get away with producing products that harm human health or the environment? How do corporations shape our society, our politics, and even our psychology? With us to untangle these questions is my guest, Barbara Freese. Barbara is an author, energy policy advocate, and environmental attorney.  After earning a law degree from New York University in 1986 she returned to her home state of Minnesota and spent a dozen years enforcing the state’s environmental laws as an Assistant Attorney General. In the mid-1990s, she litigated the science of climate change against the coal industry. She became so interested in coal’s larger impact on the world that she dug deeper into the issue, and in 2003 published the book, Coal: A Human History. An updated edition of Coal was published by Basic Books in 2016. After writing Coal, she spent years wo

Discoveries in basic science often translate into material goods, and frequently in surprising ways. Material goods, in turn, facilitate scientific progress. Therefore, science and technology advance in tandem. Today we delve into the history of materials science with the help of Ainissa Ramirez. Ainissa is a scientist and science communicator, and the author of The Alchemy of Us: How Humans and Matter Transformed One Another, published by MIT Press. 

Today we explore what mathematicians would refer to as the non-trivial intersection between science and poetry. Guiding us through these overlapping sets is a person uniquely suited to the task, the science writer Dava Sobel. Dava is the author of prominent and best-selling science history books, including Longitude, Galileo’s Daughter, The Planets, A More Perfect Heaven, and The Glass Universe. She is also the editor of Meter, the poetry series in Scientific American. Dava began her career as a science journalist in 1970. She worked as a science writer for the Cornell University News Bureau and as a reporter for the New York Times. She also wrote pieces for many other outlets, including Harvard Magazine, Omni, Science Digest, Discover, Audubon, Life, and The New Yorker. She says that her best academic credential is undoubtedly her diploma from the Bronx High School of Science, where she graduated in 1964. Dava has received numerous literary prizes in recognition of her outstanding contributions to science hi

Frogs have hopped around this planet for 200 million years. In comparison, anatomically modern humans have only been around for 200 thousand years. But the last half century has seen a tragic loss in amphibian biodiversity around the world. It seems especially striking that a group of animals that predate the dinosaurs have been devastated by modern human activities. With us today to discuss the history of discoveries in the area of amphibian declines is David Wake. David graduated from Pacific Lutheran College in 1958, and received M.S. and Ph.D. degrees from the University of Southern California in 1960 and 1964. He then taught at the University of Chicago before joining the faculty at the University of California, Berkeley in 1969. At Berkeley, David served as curator of herpetology and Director of the Museum of Vertebrate Zoology. He also served as President of the Society for the Study of Evolution, the American Society of Naturalists, and the American Society of Zoologists. In 1998, David was elected in

Chemistry has given the world the incredible diversity of fuels, pharmaceuticals, and household products that we rely on every day, along with tremendous advances in fighting infectious diseases and ensuring an abundant food supply. But the products of chemistry also include tens of thousands of toxic compounds that compromise human health, degrade the environment, and drive species to extinction. The advent of the modern environmental movement in the 1960s and 1970s produced a new field of chemistry dedicated to providing for the needs of society with less toxic and less environmentally damaging alternatives. This intellectual endeavor coalesced into the field of green chemistry. My guest, Terry Collins, is a leading green chemist and one of the founders of the field. His education includes a bachelor of science in 1974 and a PhD in 1978, both from the University of Auckland in New Zealand. He held a faculty position at the California Institute of Technology in the 1980s before joining the faculty at Carnegi

Rachel Carson alerted the world to the dangers of pollution with the publication of her book Silent Spring in 1962, and in the process, she helped to launch the environmental movement. My guest, Paul Ehrlich, alerted the world to the dangers of human population growth and resource consumption with the publication of his book The Population Bomb in 1968, and in the process, he accelerated the environmental movement. He has played a major role in that movement ever since, authoring dozens of influential books and many more articles. Ehrlich received a bachelor’s degree from the University of Pennsylvania in 1953 and a PhD from the University of Kansas in 1957. He has been a professor at Stanford University since 1959, where he is the president of the Center for Conservation Biology. He is the recipient of numerous environmental prizes, such as a MacArthur Fellowship, the John Muir Award of the Sierra Club, the Tyler Prize for Environmental Achievement, the Blue Planet Prize, and the Eminent Ecologist Award of t

Global biodiversity is in the midst of a mass extinction driven by rapid human population growth and over-consumption of resources. These forces drive habitat loss, pollution, invasive species, climate change, and the many other proximate causes of species losses. The study of these forces, and how they can be mitigated to preserve biodiversity, is the responsibility of scientists engaged in the field of conservation biology. My guest, Thomas Lovejoy, is a founding scientist of this field, and often referred to as the Godfather of Biodiversity. Tom received B.S. and Ph.D. degrees in biology at Yale. He then held many prominent positions related to conservation, including with the World Wildlife Fund, the Smithsonian Institution, the World Bank, and the Inter-American Development Bank. He served in many scientific advisory roles for the U.S. government, and as a Conservation Fellow and Explorer at Large for National Geographic. Tom is a professor in the Environmental Science and Policy department at George Mas

Nothing is more human than language, and no one has done more to advance the science of linguistics than Noam Chomsky. Noam was born in 1928, and completed undergraduate and graduate degrees at the University of Pennsylvania just after the Second World War. He earned his PhD in 1955, and by 1957, he was already publishing landmark works in linguistics that disrupted the field and fundamentally altered the understanding of language. His work also devastated the field of behaviorism, led by the likes of B.F. Skinner. Noam is known as the father of modern linguistics, but his influence extends well beyond the study of language to include fundamental applications in computer science, philosophy, cognitive science, and many other fields. Noam has taught at MIT since 1955, and at the University of Arizona since 2017.

Space exploration thrills kids and adults alike. Today I discuss the history of NASA and space science with Pam Melroy. Pam piloted the Space Shuttle missions STS-92 in 2000 and STS-112 in 2002, and she commanded STS-120 in 2007. We discuss the Mercury, Gemini, Apollo and Apollo-Soyuz programs, the Mariner 9 mission, Landsat satellites, Skylab, the Space shuttle, and the International Space Station. We also discuss scientific advances achieved in space in telemedicine, microgravity and health, protein crystal growth and drug development, and materials science, as well as the future of space science.

Freshwater ecosystems and their resident species have declined more rapidly than either terrestrial or marine systems and their species. Freshwater ecosystems face myriad stressors, from habitat loss and pollution to dams and climate change. Today I discuss the state of freshwater conservation science with Ian Harrison. Ian obtained his Ph.D. in systematic ichthyology at the University of Bristol in the UK. He has conducted research on marine and freshwater fishes in Europe, Central and South America, Africa, the Philippines, and the Central Pacific. He has worked for Conservation International and the IUCN’s Global Species Programme since 2008 and he is currently the freshwater specialist for Conservation International’s Moore Center for Science. Ian publishes extensively on the biology and conservation of fishes and the conservation of freshwater ecosystems.

Due to recent technological advances, scientists have revolutionized our understanding of human evolutionary history. What appeared to be a relatively simple story of divergence from ancient hominids is instead a tangled mess involving repeated cycles of divergence and hybridization between evolving human species. Today my guest is Jason Wilder, who researches human evolutionary genetics and genomics. We discuss the genetics of malaria resistance and parallel evolution, CCR5 deficiency and resistance to HIV infection, gene editing and the creation of designer babies, gene editing to treat disease, and introgression between modern humans and archaic forms, including Neanderthals and Denisovans. Jason received his B.A. in biology at Williams College and his Ph.D. in Ecology and Evolutionary Biology at Princeton University. He then worked at the University of Arizona and Williams before joining the faculty at Northern Arizona University, where he is a professor of genetics and the Interim Dean of the College of

The brain is the most enigmatic of organs – it is really a collection of organs that undergoes a remarkable coordinated development that is driven in part by sex steroids. Today my guest is Margaret McCarthy, one of the leading researchers on sex differences in the brain. Here, we cover the history of research on sex and the brain, including the utility of animal models, the roles of hormones and sensitive periods in brain development, masculinization vs. feminization of the brain, epigenetic regulation of sex differences in the brain, differences between the sexes in the prevalence and age of onset of mental illnesses, and even the role of politics in the field of neurobiology. Margaret received her BS and MA degrees in biology at the University of Missouri in 1981 and 1984, respectively, and her PhD in behavioral neuroscience at Rutgers University in 1989. She then worked at Rockefeller University and the National Institutes of Health before joining the faculty at the University of Maryland, where she holds

Today we explore the history of plutonium with Frank von Hippel, a retired but always active professor at Princeton University, where, in 1975, he co-founded Princeton’s Program on Science and Global Security in the Woodrow Wilson School of Public and International Affairs. In the 1980s, Frank was the chairman of the Federation of American Scientists, and in the Clinton Administration he was the Assistant Director for National Security in the White House Office of Science and Technology Policy. Frank has worked on nuclear arms control and nonproliferation since the 1980s, and received many awards for this work, including a MacArthur Fellowship. Frank received his B.S. in physics at MIT in 1959 and his Ph.D. in theoretical physics at the University of Oxford in 1962, where he was a Rhodes Scholar. Frank is also a co-author of the forthcoming book, “Plutonium: How nuclear power’s dream fuel became a nightmare.” We discuss the history of all things nuclear – the development of the bomb, the attacks on Hiroshima

We explore the history of the discovery of gravitational waves with Rai Weiss, including the relevance to special and general relativity, pulsars, supernovae, merging and binary black holes, space and time, neutron star collisions, dark matter, cosmic background radiation, gamma ray bursts, and even the viscosity of neutrinos. We also discuss really small numbers, the origin of the NSF and NASA, the LIGO scientific collaboration, the politics of science, and what all this has to do with Albert Einstein. Rai received his PhD at MIT in 1962, and taught at Tufts University and Princeton before returning to MIT. Among Rai’s many distinguished awards is the 2017 Nobel Prize in Physics, which he received along with Kip Thorne and Barry Barish “for decisive contributions to the LIGO detector and the observation of gravitational waves.”

In this supplemental episode with Matthew Meselson, I accepted his invitation to visit him in his office at Harvard, where we discussed yellow rain incidents in Southeast Asia. Meselson received his appointment as an Associate Professor of biology at Harvard in 1960 and his full professorship in 1964. He has been at Harvard ever since. Meselson has received many prominent awards throughout his career, including from the National Academy of Sciences, the Federation of American Scientists, the New York Academy of Sciences, and the Genetics Society of America, as well as the Guggenheim Fellowship and MacArthur Fellows Program Genius Award. 

Matthew Meselson organized the Herbicide Assessment Commission in 1970, which investigated the use of Agent Orange and other defoliants in Vietnam. The work of the commission helped to end Operation Ranch Hand, in which the United States sprayed nearly 20 million gallons – about 73 million liters - of herbicides and defoliants over the rainforest and mangrove forest canopies of Vietnam, Laos and Cambodia. I called Meselson to ask about his role in the Herbicide Assessment Commission, along with a host of other fascinating investigations to do with chemical and biological weapons, such as the anthrax accident in the Soviet Union and the yellow rain incident in Laos.  I also asked him about the U.S. Army’s insane plan in 1969 to ship 800 railroad cars filled with 27,000 tons of poison-gas weapons from the Rocky Mountain Arsenal to New Jersey for disposal at sea. Meselson completed his Ph.D. in 1957 under Linus Pauling at CalTech.  In 1958, in a classic experiment, he and Frank Stahl showed that DNA is replicate