Life By Design Podcast

#373 Fish Oil For Major Depressive Disorder?

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Synopsis

The subcommittee of the International Society for Nutritional Psychiatry Research organized an expert panel, conducted a literature review and a Delphi process to develop a consensus-based practice guideline for clinical use of polyunsaturated fatty acids in Major Depressive Disorder.   This systematic review of the published literature emphasized randomized controlled trials, systematic reviews, and meta-analyses.   As it currently stands, treatment for major depressive disorder is only mildly successful with many adverse and unpredictable effects.   The goal of the panel was to create guidelines that would help create patient outcomes that are more tolerable and efficacious.    What We Covered Several lines of evidence have suggested the efficacy of n–3 PUFAs as a preventive and treatment strategy in major depressive disorder, from epidemiological and case-controlled studies to randomized-controlled trials and meta-analyses. According to the currently available randomized controlled trials, the starting d