Snippit Sports Science Podcast

Snippit 73 ► Genetic Variation in Caffeine Metabolism

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Synopsis

  We need the help of listeners like you to keep the podcast going!Please help support the podcast:► https://www.patreon.com/snippitscience      https://www.ncbi.nlm.nih.gov/pubmed/29971434   JAMA Intern Med. 2018 Aug 1;178(8):1086-1097. doi: 10.1001/jamainternmed.2018.2425   Association of Coffee Drinking With Mortality by Genetic Variation in Caffeine Metabolism: Findings From the UK Biobank.   Loftfield E, Cornelis MC, Caporaso N, Yu K, Sinha R, Freedman N.   Abstract   IMPORTANCE: Prospective cohorts in North America, Europe, and Asia show consistent inverse associations between coffee drinking and mortality, including deaths from cardiovascular disease and some cancers. However, concerns about coffee, particularly among people with common genetic polymorphisms affecting caffeine metabolism and among those drinking more than 5 cups per day, remain.   OBJECTIVE: To evaluate associations of coffee drinking with mortality by genetic caffeine metabolism score.   DESIGN, SETTING, AND PARTICIPANTS: The UK B