Science Friday

Placenta Research May Help Explain Pregnancy Loss

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Synopsis

Content warning: This interview includes discussion of miscarriage and pregnancy loss, and may be triggering for some listeners.The placenta is an incredible body part. It’s the only organ grown temporarily, created during pregnancy and discarded after birth. It has the enormous job of supporting the growth of a fetus, protecting it from infection and inflammation. When something goes wrong with the placenta, it can result in the loss of a baby.For something that can be so devastating to expectant parents, miscarriages are incredibly normal. Of the 5 million pregnancies each year in the United States, about 1 million end in miscarriage, categorized as a loss before 20 weeks of gestation. About 20,000 pregnancies end in stillbirth during the later stages of gestation.Often, after a pregnancy loss, doctors tell parents that the cause is unexplained. This can lead to feelings of failure and guilt, even though pregnancy loss is almost always out of a person’s control.Dr. Harvey Kliman, director of the Yale School