Science Friday

If given final approval by the FDA, this sickle-cell treatment would be the first to use gene-editing CRISPR technology on humans. Also, gene variants inherited from Neanderthals can impact pain tolerance in modern humans.  FDA Panel Clears Way For CRISPR-Based Sickle Cell TreatmentAn FDA committee cleared the way for a revolutionary cure for sickle cell disease this week. If given final approval, the treatment would be the first to use CRISPR gene editing in humans. Sickle cell disease is caused by a genetic mutation that causes blood cells to develop into crescent or “sickle” shapes. The extremely painful and often deadly disease disproportionately affects Black and African American people.Ira talks with Vox staff writer Umair Irfan about the new sickle cell treatment and other top science news of the week, including the link between the auto worker strike and a clean energy transition; new evidence about the moon’s origin; and why starfish don’t have arms. Your Pain Tolerance May Have Been Passed Down from