Science On Top

SoT 155: The Grumpiest Mouse

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Synopsis

Twenty-seven months ago the "Mississippi Baby" stopped HIV treatment and was believed to be free of the virus. Unfortunately, that changed this month when test showed the virus is back. It had gone into hiding and the now four-year-old girl will face years, possibly her whole life, on antiretroviral therapy. A scientist at a CDC research centre found a cardboard box containing six vials of the smallpox virus in a storage room. The vials are believed to have been left there since the 1950s, and there is always a possibility that there are other long-forgotten samples of the virus elsewhere. A study of mice that attempted to replicate the Dutch Winter Hunger have found that stresses on a mother can have epigenetic effects, altering gene expressions across multiple generations. When experimental stem cell therapies go wrong: an 18 year old paraplegic had stem cells from her nose placed in her spine as part of a trial. Eight years later, the cells had grown into a mass of nasal tissue containing a thick, mucous-l