Angel Invest Boston

Invest Alongside Boston's Top Angels: Our Syndicates Seasoned entrepreneur Nancy Briefs on her startup’s daring swing at Type 2 diabetes. AltrixBio is creating a pill that simulates the benefit of the best gastric bypass surgery: remission of diabetes in 80 percent of cases. With co-founders Jeff Karp and Ali Tavakoli, she is re-purposing an existing treatment with a great safety profile to address this daunting problem. Highlights include: Nancy Briefs, co-founded 7 companies and managed, or been on the board of, several others. Together with Dr. Karp and Dr. Tavakoli of Brigham & Women’s Hospital, Nancy co-founded AltrixBio to emulate the results of gastric bypass in a pill. Sal saw Nancy pitch at MIT Angels and Walnut Ventures and was impressed. Ali Tavakoli, M.D. performs the Roux-en-Y procedure which is the gastric bypass operation with the best record of success. Tavakoli and others observed that diabetic patients who experienced the procedure had their Type 2 diabetes go into remission about 80 pe