The Ezra Klein Show

The chemistry of connection

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Synopsis

Could our brains make us less lonely? Sean Illing talks with psychiatrist and author Julie Holland, whose new book Good Chemistry takes on the crisis of disconnectedness we face today. They discuss the brain chemistry of attachment and human connection, how psychedelics can be used both in therapeutic contexts and to help us feel more connected to others, and the toll that this crisis of isolation can take on us — emotionally, physically, and spiritually. Host: Sean Illing (@seanilling), host, The Gray Area Guest: Julie Holland, MD (@BellevueDoc), psychiatrist; medical advisor to MAPS; author References:  Good Chemistry: The Science of Connection from Soul to Psychedelics by Julie Holland (Harper; 2022) "Work and the Loneliness Epidemic" by Vivek Murthy (Harvard Business Review; Sept. 26, 2017) "Loneliness in U.S. Subsides From Pandemic High" by Dan Witters (Gallup; Apr. 4) The Red Book by Carl Jung (written from 1914–1930; pub. Norton; 2009) "People would rather be electrically shocked than left al